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Abnova/ADD1 (phospho S726) polyclonal antibody/1kit/PAB25323
  • Abnova/ADD1 (phospho S726) polyclonal antibody/1kit/PAB25323

Abnova/ADD1 (phospho S726) polyclonal antibody/1kit/PAB25323

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貨號(hào): PAB25323
品牌: Abnova
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  • 詳情
  • 使用說(shuō)明
  • 常見(jiàn)問(wèn)題
      • Specification
      • Gene Info
      • Disease
      • Related Products
      • List All
      • Specification
      • Product Description:
      • Rabbit polyclonal antibody raised against synthetic phosphopeptide of ADD1.
      • Immunogen:
      • Synthetic phosphopeptide corresponding to residues surrounding S726 of human ADD1.
      • Sequence:
      • T-P-Sp-F-L
      • Host:
      • Rabbit
      • Reactivity:
      • Human, Mouse, Rat
      • Form:
      • Liquid
      • Purification:
      • Affinity purification
      • Recommend Usage:
      • Western Blot (1:500-1:1000)Immunohistochemistry (1:50-100)The optimal working dilution should be determined by the end user.
      • Storage Buffer:
      • In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
      • Storage Instruction:
      • Store at -20°C.Aliquot to avoid repeated freezing and thawing.
      • Note:
      • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • Western Blot (Cell lysate)
      • Western Blot (Cell lysate)
      • Western blot analysis of extract from HT-29 cells untreated or treated with Doxorubicin (1 mM, 30 min), using ADD1 (phospho S726) polyclonal antibody (Cat # PAB25323).
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using ADD1 (phospho S726) polyclonal antibody (Cat # PAB25323).
      • Application Image
      • Western Blot (Cell lysate)
      • Western Blot (Cell lysate)
      • enlarge
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • enlarge
      • Gene Information
      • Entrez GeneID:
      • 118
      • Protein Accession#:
      • P35611
      • Gene Name:
      • ADD1
      • Gene Alias:
      • ADDA,MGC3339,MGC44427
      • Gene Description:
      • adducin 1 (alpha)
      • Omim ID:
      • 102680, 145500
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. [provided by RefSeq
      • Other Designations:
      • OTTHUMP00000151164,OTTHUMP00000151165,erythrocyte adducin alpha subunit
      • Related Disease
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      • Arteriosclerosis
      • Atherosclerosis
      • Atherosclerosis
      • Brain Ischemia
      • Cardiovascular Diseases
      • Carotid Artery Diseases
      • Cerebral Hemorrhage
      • Cerebral Palsy
      • Cerebrovascular Accident
      • Cerebrovascular Disorders
      • Cognition Disorders
      • Constriction, Pathologic
      • Coronary Artery Disease
      • Coronary Disease
          • ... see more
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