Immunogen | ViableMeningococcusgroupB(strain355). |
Clone | 2-2B |
Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
Host | Mouse |
Specificity | Reactswithalpha2-8linkedneuraminicacid(NeuAc-alpha2-8)nwithn>10.Thispolymerisusuallytermedpolysialicacid(PSA).InvertebratesPSAislinkedtoneuralcelladhesionmolecule(NCAM,CD56),inbacteriaitisassociatedwithcapsulaofmeningococcusstraingroupB. |
Isotype | IgM |
SpeciesReactivity | |
SpeciesReactivityNote | ThemonoclonalworkswellonallspeciesexpressingPSA-NCAMincludingmouse. |
AntibodyType | MonoclonalAntibody |
EntrezGeneNumber | |
GeneSymbol | - NCAM1
- CD56
- NCAM-140
- NCAM
- NCAM-120
- MSK39
|
PurificationMethod | Unpurified |
UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:P13592#Thisproteinisacelladhesionmoleculeinvolvedinneuron-neuronadhesion,neuritefasciculation,outgrowthofneurites,etc.|P13591#Thisproteinisacelladhesionmoleculeinvolvedinneuron-neuronadhesion,neuritefasciculation,outgrowthofneurites,etc. SIZE:761aminoacids;83770Da SUBCELLULARLOCATION:Cellmembrane;Lipid-anchor,GPI-anchor. DOMAIN:SwissProt:P13592 SIMILARITY:SwissProt:P13592##Contains2fibronectintype-IIIdomains.&Contains5Ig-likeC2-type(immunoglobulin-like)domains.|P13591##Contains2fibronectintype-IIIdomains.&Contains5Ig-likeC2-type(immunoglobulin-like)domains. |
MolecularWeight | 150-300kDa |