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Abnova/ABL1 (Human) Cell-Based ELISA Kit/1kit/KA2553
  • Abnova/ABL1 (Human) Cell-Based ELISA Kit/1kit/KA2553

Abnova/ABL1 (Human) Cell-Based ELISA Kit/1kit/KA2553

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貨號(hào): KA2553
品牌: Abnova
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  • 詳情
  • 使用說明
  • 常見問題
      • Specification
      • Product Description:
      • ABL1 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of ABL1 expression in cultured cells.
      • Reactivity:
      • Human, Mouse, Rat
      • Storage Instruction:
      • Store the kit at 4°C.
      • Protocol:
      • PDF DownloadProtocol Download
      • Suitable Sample:
      • Attached Cell, Loosely Attached Cell, Suspension Cell
      • Label:
      • HRP-conjugated
      • Detection Method:
      • Colorimetric
      • Regulation Status:
      • For research use only (RUO)
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • Qualitative
      • Application Image
      • Qualitative
      • Gene Information
      • Entrez GeneID:
      • 25
      • Protein Accession#:
      • P00519
      • Gene Name:
      • ABL1
      • Gene Alias:
      • ABL,JTK7,bcr/abl,c-ABL,p150,v-abl
      • Gene Description:
      • c-abl oncogene 1, receptor tyrosine kinase
      • Omim ID:
      • 189980
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response.Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene.The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia.The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq
      • Other Designations:
      • Abelson murine leukemia viral (v-abl) oncogene homolog 1,OTTHUMP00000022375,OTTHUMP00000022376,bcr/c-abl oncogene protein,proto-oncogene tyrosine-protein kinase ABL1,v-abl Abelson murine leukemia viral oncogene homolog 1
      • Gene Pathway
      • Axon guidance
      • Cell cycle
      • Chronic myeloid leukemia
      • ErbB signaling pathway
      • Neurotrophin signaling pathway
      • Pathogenic Escherichia coli infection - EHEC
      • Pathways in cancer
      • Related Disease
      • Adenocarcinoma
      • Alzheimer Disease
      • Alzheimer disease
      • Breast cancer
      • Breast Neoplasms
      • Cardiovascular Diseases
      • Chronic Disease
      • Diabetes Complications
      • Esophageal Neoplasms
      • Genetic Predisposition to Disease
      • HIV Infections
      • Leukemia, chronic myeloid
      • Leukemia, Myelogenous, Chronic, BCR-ABL Positive
      • Leukemia, Myeloid
      • Leukemia, Myeloid, Chronic
      • Metabolic Syndrome X
      • Neoplasms
      • Osteoporosis
      • Ovarian cancer
        • ... see more
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