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Abnova/ABCG8 (Human) Recombinant Protein/1kit/H00064241-G01
  • Abnova/ABCG8 (Human) Recombinant Protein/1kit/H00064241-G01

Abnova/ABCG8 (Human) Recombinant Protein/1kit/H00064241-G01

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貨號(hào): H00064241-G01
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  • 詳情
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  • 常見問題
      • Specification
      • Gene Info
      • Pathway
      • Disease
      • Related Products
      • List All
      • Specification
      • Product Description:
      • Human ABCG8 full-length ORF (ADR83246.1) recombinant protein without tag.
      • Sequence:
      • MAGKAAEERGLPKGATPQHTSGLQDRLFSSESDNSLYFTYSGQPNTLEVRDLNYQVDLASQVPWFEQLAQFKMPWTSPSCQNSCELGIQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQPSSPQLVRKCVAHVRQHNQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRVGNMYVRGLSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCPRYSNPADFYVDLTSIDRRSREQELATREKAQSLAALFLEKVRDLDDFLWKAETKDLDEDTCVESSVTPLDTNCLPSPTKMPGAVQQFTTLIRRQISNDFRDLPTLLIHGAEACLMSMTIGFLYFGHGSIQLSFMDTAALLFMIGALIPFNVILDVISKCYSERAMLYYELEDGLYTTGPYFFAKILGELPEHCAYIIIYGMPTYWLANLRPGLQPFLLHFLLVWLVVFCCRIMALAAAALLPTFHMASFFSNALYNSFYLAGGFMINLSSLWTVPAWISKVSFLRWCFEGLMKIQFSRRTYKMPLGNLTIAVSGDKILSAMELDSYPLYAIYLIVIGLSGGFMVLYYVSLRFIKQKPSQDW
      • Host:
      • Wheat Germ (in vitro)
      • Theoretical MW (kDa):
      • 74.1
      • Form:
      • Liquid
      • Preparation Method:
      • in vitro wheat germ expression system with proprietary liposome technology
      • Purification:
      • None
      • Recommend Usage:
      • Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
      • Storage Buffer:
      • 25 mM Tris-HCl of pH8.0 containing 2% glycerol.
      • Storage Instruction:
      • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
      • Note:
      • Best use within three months from the date of receipt of this protein.
      • Interspecies Antigen Sequence:
      • Mouse (81); Rat (79)
      • Datasheet:
      • PDF DownloadDownload
      • Publication Reference
      • 1.
      • Production and partial purification of membrane proteins using a liposome-supplemented wheat cell-free translation system.Nozawa A, Ogasawara T, Matsunaga S, Iwasaki T, Sawasaki T, Endo Y. BMC Biotechnol. 2011 Apr 11;11:35.
      • Applications
      • Antibody Production
      • Application Image
      • Antibody Production
      • Gene Information
      • Entrez GeneID:
      • 64241
      • GeneBank Accession#:
      • HQ258492.1
      • Protein Accession#:
      • ADR83246.1
      • Gene Name:
      • ABCG8
      • Gene Alias:
      • GBD4,MGC142217,STSL
      • Gene Description:
      • ATP-binding cassette, sub-family G (WHITE), member 8
      • Omim ID:
      • 210250, 605460
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq
      • Other Designations:
      • ATP-binding cassette sub-family G member 8,ATP-binding cassette, subfamily G, member 8,sterolin 2
      • Gene Pathway
      • ABC transporters
      • Related Disease
      • Atherosclerosis
      • Atherosclerosis
      • Biliary Tract Neoplasms
      • Cardiovascular Diseases
      • Cholelithiasis
      • Coronary Artery Disease
      • Coronary Disease
      • Diseases in Twins
      • Dyslipidemias
      • Gallbladder Neoplasms
      • Gallstones
      • Genetic Predisposition to Disease
      • Hypercholesterolemia
      • Hyperlipidemias
      • Hyperlipoproteinemia Type II
      • Insulin Resistance
      • Kidney Failure, Chronic
      • Lung Neoplasms
      • Metabolic Syndrome X
          • ... see more
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