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Abnova/ACO1 (Human) IP-WB Antibody Pair/1kit/H00000048-PW1
  • Abnova/ACO1 (Human) IP-WB Antibody Pair/1kit/H00000048-PW1

Abnova/ACO1 (Human) IP-WB Antibody Pair/1kit/H00000048-PW1

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貨號: H00000048-PW1
品牌: Abnova
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  • 詳情
  • 使用說明
  • 常見問題
      • Specification
      • Product Description:
      • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
      • Reactivity:
      • Human
      • Quality Control Testing:
      • Immunoprecipitation-Western Blot (IP-WB)QC Testing of H00000048-PW1Immunoprecipitation of ACO1 transfected lysate using mouse monoclonal anti-ACO1 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-ACO1.
      • Supplied Product:
      • Antibody pair set content:1. Antibody pair for IP: mouse monoclonal anti-ACO1 (300 ug)2. Antibody pair for WB: rabbit polyclonal anti-ACO1 (50 ul)
      • Storage Instruction:
      • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
      • MSDS:
      • PDF DownloadDownload
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • Immunoprecipitation-Western Blot
      • PDF DownloadProtocol Download
      • Application Image
      • Immunoprecipitation-Western Blot
      • Gene Information
      • Entrez GeneID:
      • 48
      • Gene Name:
      • ACO1
      • Gene Alias:
      • ACONS,IREB1,IREBP,IREBP1,IRP1
      • Gene Description:
      • aconitase 1, soluble
      • Omim ID:
      • 100880
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs).IREs are stem-loop structures found in the 5" UTR of ferritin mRNA, and in the 3" UTR of transferrin receptor mRNA.The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA.Thus, IREB1 plays a central role in cellular iron homeostasis.It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes. [provided by RefSeq
      • Other Designations:
      • OTTHUMP00000021176,OTTHUMP00000021177,OTTHUMP00000045233,aconitase 1,aconitate hydratase,citrate hydro-lyase,ferritin repressor protein,iron regulatory protein 1,iron-responsive element binding protein 1
      • Gene Pathway
      • Biosynthesis of alkaloids derived from histidine and purine
      • Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
      • Biosynthesis of alkaloids derived from shikimate pathway
      • Biosynthesis of alkaloids derived from terpenoid and polyketide
      • Biosynthesis of phenylpropanoids
      • Biosynthesis of plant hormones
      • Biosynthesis of terpenoids and steroids
      • Citrate cycle (TCA cycle)
      • Glyoxylate and dicarboxylate metabolism
      • Metabolic pathways
      • Reductive carboxylate cycle (CO2 fixation)
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