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Abnova/BCL6 Split FISH Probe/1kit/FS0068
  • Abnova/BCL6 Split FISH Probe/1kit/FS0068

Abnova/BCL6 Split FISH Probe/1kit/FS0068

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貨號(hào): FS0068
品牌: Abnova
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  • 詳情
  • 使用說(shuō)明
  • 常見(jiàn)問(wèn)題
      • Specification
      • Gene Info
      • Disease
      • Related Products
      • List All
      • Specification
      • Product Description:
      • Labeled FISH probes for identification of gene split using Fluoresecent In Situ Hybridization Technique. (Technology)
      • Form:
      • Liquid
      • Quality Control Testing:
      • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.QC Testing of FS0068
      • Supplied Product:
      • DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
      • Storage Instruction:
      • Store at 4°C in the dark.
      • Probe 1:Size:Fluorophore:Location:
      • BCL6Approximately 600kbTexas Red3q27.3
      • Probe 2:Size:Fluorophore:Location:
      • BCL6Approximately 740kbFITC3q27.3
      • Origin:
      • Human
      • Source:
      • Genomic DNA
      • Notice:
      • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
      • Regulation Status:
      • For research use only (RUO)
      • Probe Position:
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • Fluorescent In Situ Hybridization (Cell)
      • PDF DownloadProtocol Download
      • Application Image
      • Fluorescent In Situ Hybridization (Cell)
      • Gene Information
      • Entrez GeneID:
      • 604
      • Gene Name:
      • BCL6
      • Gene Alias:
      • BCL5,BCL6A,LAZ3,ZBTB27,ZNF51
      • Gene Description:
      • B-cell CLL/lymphoma 6
      • Omim ID:
      • 109565
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq
      • Other Designations:
      • B-cell lymphoma 6 protein,B-cell lymphoma 6 protein transcript,cys-his2 zinc finger transcription factor,lymphoma-associated zinc finger gene on chromosome 3,zinc finger protein 51,zinc finger transcription factor BCL6S
      • Related Disease
      • Adenocarcinoma
      • Central Nervous System Neoplasms
      • Esophageal Neoplasms
      • Genetic Predisposition to Disease
      • Hematologic Diseases
      • HIV Infections
      • Hodgkin Disease
      • Kidney Failure, Chronic
      • Leukemia, chronic myeloid
      • Leukemia, Myelogenous, Chronic, BCR-ABL Positive
      • Lung Neoplasms
      • Lymphoma, AIDS-Related
      • Lymphoma, B-Cell
      • Lymphoma, Follicular
      • Lymphoma, Large B-Cell, Diffuse
      • Lymphoma, Large-Cell, Diffuse
      • Lymphoma, Non-Hodgkin
      • Lymphoproliferative Disorders
      • Neovascularization, Pathologic
          • ... see more
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