當(dāng)前位置 ： Millipore >>> Millipore/CBL275 | Anti-Neural Adhesion Molecule L1 Antibody, clone UJ127.11/CBL275/100 µg
Millipore/CBL275 | Anti-Neural Adhesion Molecule L1 Antibody, clone UJ127.11/CBL275/100 µg
  • Millipore/CBL275 | Anti-Neural Adhesion Molecule L1 Antibody, clone UJ127.11/CBL275/100 µg

Millipore/CBL275 | Anti-Neural Adhesion Molecule L1 Antibody, clone UJ127.11/CBL275/100 µg

價格: 試用 市場價: 0.00
貨號: CBL275
品牌: Millipore
規(guī)格
數(shù)量
庫存(0)
特別 提示
代購產(chǎn)品：無質(zhì)量問題不接受退換貨，下單前請仔細核對信息。
下單后請及時聯(lián)系客服核對商品價格，訂單生效后再付款。
資深產(chǎn)品顧問
咨詢顧問

全國免費服務(wù)熱線

4000-520-616

  • 自營商城 一站式服務(wù)
  • 廠家直采 剔除溢價
  • 品質(zhì)甄選 正品保證
  • 嚴控流程 只做188精品
  • 極速物流 如約送貨
  • 詳情
  • 使用說明
  • 常見問題
    • Description
      CatalogueNumberCBL275
      BrandFamilyChemicon®
      TradeName
      • Chemicon
      DescriptionAnti-NeuralAdhesionMoleculeL1Antibody,cloneUJ127.11
      AlternateNames
      • CD171
      • N-CAML1
      BackgroundInformationFamiliesofadhesionmoleculeswhichsharecommoncarbohydratedomainsdoexist,despitethestructuralandfunctionaldiversityoftheseglycoproteins.TheseincludetheCa2+-independentneuraladhesionmolecules:N-CAM,myelinassociatedglycoprotein(MAG)andL1.L1isinvolvedinneuron-neuronadhesion,neuritefasciculation,outgrowthofneurites,cerebellargranulecellmigration,neuriteoutgrowthonSchwanncellsandinteractionsamongepithelialcellsofintestinalcrypts
      ProductInformation
      FormatPurified
      PresentationThemonoclonalispresentedataconcentrationof100μg/1mlinphosphatebufferedsalinecontaining10mMsodiumazideand1mg/mlbovineserumalbumin.Werecommendthateachlaboratorydetermineanoptimumworkingtitreforuseinitsparticularapplication.
      StorageandShippingInformation
      StorageConditionsForusewithin1monthofpurchasestoreat+4°C,forlongtermstoragealiquotantibodyintosmallvolumesandstoreat-20°C.
      Applications
      ApplicationDetectNeuralAdhesionMoleculeL1usingthisAnti-NeuralAdhesionMoleculeL1Antibody,cloneUJ127.11validatedforuseinFC,IP,WB,IH.
      KeyApplications
      • FlowCytometry
      • Immunoprecipitation
      • WesternBlotting
      • Immunohistochemistry
      ApplicationNotesFlowCytometry.

      Westernblotting.

      Immunohistochemistryonfrozensections.

      Immunoprecipitation.

      Optimalworkingdilutionsmustbedeterminedbytheenduser.
      BIOLOGicalInformation
      ImmunogenHomogenateof16weekhumanfoetalbraincells.
      CloneUJ127.11
      HostMouse
      SpecificityTheantibodyreactswiththe220-240kDaglycoproteinL1moleculewhichisexpressedinneuraltissues,neuroblastomaandmedulloblastoma.L1NCAMexpressionalsooccursoncellsofmyelomonocyticandlymphoidorigin.

      FUSIONPARTNER:P3-X63-Ag8.653myelomacellline.
      IsotypeIgG1
      SpeciesReactivity
      • Human
      AntibodyTypeMonoclonalAntibody
      GeneSymbol
      • VCAM1
      • INCAM-100
      • MGC99561
      • CD106
      • DKFZp779G2333
      • L1CAM
      UniProtNumber
      UniProtSummaryFunction:Celladhesionmoleculewithanimportantroleinthedevelopmentofthenervoussystem.Involvedinneuron-neuronadhesion,neuritefasciculation,outgrowthofneurites,etc.Bindstoaxoninonneurons.
      Subcellularlocation:Cellmembrane;Single-passtypeImembraneprotein.
      Involvementindisease:DefectsinL1CAMarethecauseofhydrocephalusduetostenosisoftheaqueductofSylvius(HSAS)[MIM:307000].Hydrocephalusisaconditioninwhichabnormalaccumulationofcerebrospinalfluidinthebraincausesincreasedintracranialpressureinsidetheskull.Thisisusuallyduetoblockageofcerebrospinalfluidoutflowinthebrainventriclesorinthesubarachnoidspaceatthebaseofthebrain.Inchildrenistypicallycharacterizedbyenlargementofthehead,prominenceoftheforehead,brainatrophy,mentaldeterioration,andconvulsions.Inadultsthesyndromeincludesincontinence,imbalance,anddementia.HSASischaracterizedbymentalretardationandenlargedbrainventricles.
      DefectsinL1CAMarethecauseofmentalretardation-aphasia-shufflinggait-adductedthumbssyndrome(MASA)[MIM:303350];alsoknownascorpuscallosumhypoplasia,psychomotorretardation,adductedthumbs,spasticparaparesis,andhydrocephalusorCRASHsyndrome.MASAisanX-linkedrecessivesyndromewithahighlyvariableclinicalspectrum.Mainclinicalfeaturesincludespasticityandhyperreflexiaoflowerlimbs,shufflinggait,mentalretardation,aphasiaandadductedthumbs.Thefeaturesofspasticityhavebeenreferredtoascomplicatedspasticparaplegiatype1(SPG1).Somepatientsmanifestcorpuscallosumhypoplasiaandhydrocephalus.Inter-andintrafamilialvariABIlityisverywide,suchthatpatientswithhydrocephalus,MASA,SPG1,andagenesisofcorpuscallosumcanbepresentwithinthesamefamily.
      DefectsinL1CAMarethecauseofspasticparaplegiaX-linkedtype1(SPG1)[MIM:303350].Spasticparaplegiaisadegenerativespinalcorddisordercharacterizedbyaslow,gradual,progressiveweaknessandspasticityofthelowerlimbs.
      DefectsinL1CAMmaycontributetoHirschsprungdisease(HSCR)[MIM:142623].ItmaydosobymodifyingtheeffectsofaHirschsprungdisease-associatedgenetocauseintestinalaganglionosis.
      DefectsinL1CAMareacauseofpartialagenesisofthecorpuscallosum[MIM:304100];aX-linkeddisorder.
      Sequencesimilarities:Belongstotheimmunoglobulinsuperfamily.L1/neurofascin/NgCAMfamily.
      Contains5fibronectintype-IIIdomains.
      Contains6Ig-likeC2-type(immunoglobulin-like)domains.
      PhysicochemicalInformation
      Dimensions
      MaterialsInformation
      MaterialsInformation
    售后保障
    螞蟻淘生物188，秉承螞蟻淘一貫的嚴謹態(tài)度，由螞蟻淘公司專業(yè)人員負責(zé)品控、采購、物流、銷售、售后，保障正品優(yōu)質(zhì)。以“快速好省，為科研提供好產(chǎn)品、好價格”為理念，直接鏈接原廠家，從全國各地原制造商嚴格挑選188款科研精品，剔除品牌溢價，188生物新電商，把好的產(chǎn)品帶給科研！? 力求給你最優(yōu)質(zhì)的商品。
  • Q：生物188產(chǎn)品正品保障嗎？
    A：生物188質(zhì)量把控人員具有十年的從業(yè)經(jīng)驗，在業(yè)界享有良好的口碑；自營商城，直接從廠家采購， 自己的團隊負責(zé)國際物流和清關(guān)，中間沒有第三方，所有流程嚴格把控，100%保證正品，假一罰十。

    Q：下單后可以修改訂單嗎？
    A：下單后的商品付款之前可以修改；訂單付款成功，需要聯(lián)系我們客服進行修改；客服電話：4000-520-616

    Q：可以開發(fā)票嗎？
    A：本網(wǎng)站所售商品都是正規(guī)清關(guān)，均開具16%正規(guī)發(fā)票，發(fā)票金額含配送費金額，另有說明的除外。

    Q：商品幾天可以發(fā)貨？
    A：生物188商品，全部現(xiàn)貨銷售，付款后即可發(fā)貨,一般一周內(nèi)送達！

    Q：如何聯(lián)系商家？
    A：有任何問題夠可以電話咨詢我們，全國24小時免費服務(wù)熱線：4000-520-616 或聯(lián)系我們的在線客服QQ：1570468124

    Q：收到的商品少了/發(fā)錯了怎么辦？
    A：同個訂單購買多個商品可能會分為一個以上包裹發(fā)出，可能不會同時送達，建議查看訂單詳情是否是 部分發(fā)貨狀態(tài)；如未收到，可聯(lián)系在線客服或者致電4000-520-616。

    Q：退換貨/維修需要多長時間？
    A：一般情況下，退貨處理周期為客戶收到產(chǎn)品一個月內(nèi)（以快遞公司顯示簽收時間為準(zhǔn)），包裝規(guī)格、 數(shù)量、品種不符，外觀毀損、短缺或缺陷，請在收到貨24小時內(nèi)申請退換貨；特殊商品以合同條款為準(zhǔn)。

何為188

極簡而嚴謹，我們僅銷售188款生物醫(yī)學(xué)科研用品，款款都是爆款；因為少所以聚焦，聚焦甄選每一款產(chǎn)品，聚焦服務(wù)每一位客戶!

關(guān)注我們 :

點擊QQ聯(lián)系我們
生物188微信

關(guān)注188微信公眾號

獲取最新優(yōu)惠活動通知

  • 品質(zhì)甄選，正品保證

  • 自營電商，廠家直采

  • 極簡主義，188精品