當前位置 : Millipore >>> Millipore/ABN27 | Anti-GRIP-1 Antibody, CT/ABN27/100 µg
Millipore/ABN27 | Anti-GRIP-1 Antibody, CT/ABN27/100 µg
  • Millipore/ABN27 | Anti-GRIP-1 Antibody, CT/ABN27/100 µg

Millipore/ABN27 | Anti-GRIP-1 Antibody, CT/ABN27/100 µg

價格: ¥4188.00 市場價: 6980.00

貨號: ABN27
品牌: Millipore
規(guī)格
數(shù)量
庫存(0)
特別 提示
代購產(chǎn)品:無質量問題不接受退換貨,下單前請仔細核對信息。
下單后請及時聯(lián)系客服核對商品價格,訂單生效后再付款。
資深產(chǎn)品顧問
咨詢顧問

全國免費服務熱線

4000-520-616


  • 自營商城 一站式服務
  • 廠家直采 剔除溢價
  • 品質甄選 正品保證
  • 嚴控流程 只做188精品
  • 極速物流 如約送貨
  • 詳情
  • 使用說明
  • 常見問題
    • Description
      CatalogueNumberABN27
      Replaces06-986
      DescriptionAnti-GRIP-1Antibody,CT
      AlternateNames
      • glutamatereceptorinteractingprotein1
      • glutamatereceptor-interactingprotein1
      BackgroundInformationGlutamatereceptorinteractingprotein-1(GRIP-1)isamulti-PDZdomainscaffoldproteinandamemberofthesteroidreceptorcoactivator(SRC)familyofproteins.GRIP-1interactsandmaneuverskinesinheavychainstodendritesbyactingasthepowersourceforAMPAreceptors.Duringinitialstagesofembryonicdevelopment,GRIP-1isessentialfortypicalcell-matrixinteractions.
      ProductInformation
      FormatAffinityPurified
      Control
      • Ratbraincytosoltissuelysate
      PresentationPurifiedrabbitpolyclonalinbuffercontaining0.1MTris-Glycine(pH7.4),150mMNaClwith0.05%sodiumazide.
      StorageandShippingInformation
      StorageConditionsStablefor1yearat2-8°Cfromdateofreceipt.
      Applications
      ApplicationDetectGRIP-1usingthisAnti-GRIP-1Antibody,C-terminusvalidatedforuseinWB,IP,IH(P).
      KeyApplications
      • WesternBlotting
      • Immunoprecipitation
      • Immunohistochemistry(Paraffin)
      ApplicationNotesImmunoprecipitationAnalysis:10μgfromapreviouslotimmunoprecipitatedGRIP-1fromratbraincytosoltissuelysate.

      ImmunohistochemistryAnalysis:1:300dilutionfromapreviouslotdetectedGRIP-1inratbraincells.
      BIOLOGicalInformation
      ImmunogenKLH-conjugatedlinearpeptidecorrespondingtotheC-terminusofratGRIP-1.
      EpitopeC-terminus
      ConcentrationPleaserefertotheCertificateofAnalysisforthelot-specificconcentration.
      HostRabbit
      SpecificityThisantibodyrecognizesGRIP-1attheC-terminus.
      SpeciesReactivity
      • Rat
      • Human
      • Mouse
      • Chimpanzee
      SpeciesReactivityNoteDemonstratedtoreactwithrat.Predictedtoreactwithhuman,mouse,andchimpanzeebasedon100%sequencehomology.
      AntibodyTypePolyclonalAntibody
      EntrezGeneNumber
      EntrezGeneSummaryBindstotheliprin-alphaSVD2familyofproteinstomediatesynaptictargetingofAMPAreceptors;mayplayaroleinpresynapticandpostsynapticmaturation[RGD].
      GeneSymbol
      • GRIP
      • GRIP-1
      • GRIP1
      • CT
      PurificationMethodAffinityPurfied
      UniProtNumber
      UniProtSummaryFUNCTION:Mayplayaroleasalocalizedscaffoldfortheassemblyofamultiproteinsignalingcomplexandasmediatorofthetraffickingofitsbindingpartnersatspecificsubcellularlocationinneurons.

      SUBUNITSTRUCTURE:InteractswithEFNB1,EPHA7,EPHB2,EFNB3,KIF5A,KIF5C,KIF5BandtheC-terminaltailofPRLHR.FormsaternarycomplexwithGRIA2andCSPG4(Bysimilarity).CanformhomomultimersorheteromultimerswithGRIP2.InteractswithGRIA2,GRIA3,GRIPAP1/GRASP1,PPFIA1,PPFIA4,FRAS1,PLCD4,PTPRFandliprins-alpha.InteractswithSLC30A9(Bysimilarity).

      SUBCELLULARLOCATION:Cytoplasm.Endomembranesystem;Peripheralmembraneprotein.Celljunction?synapse?postsynapticcellmembrane.Celljunction?synapse?postsynapticcellmembrane?postsynapticdensity.Endoplasmicreticulummembrane;Peripheralmembraneprotein(Potential).Note:Membrane-associatedwithvesicles,peri-Golgicomplexesandendoplasmicreticulum.Enrichedinpost-synapticplasmamembraneandpost-synapticdensities.

      TISSUESPECIFICTY:Expressedinbrain,testisandretina.Inbrainhighlyexpressedintheolfactorybulb,cortexandhyppocampusandlowerlevelinthalamus,cerebellumandspinalcord.Inbrainitisfoundintheperikaryon,dendrites,dendriticshafts,dendriticspinesand,excitatoryandinhibitorysynapsesofneurons.Inretina,itismostabundantintheplexiformlayersthaninperikarya.

      DEVELOPMENTALSTAGE:DetectedinearlyembryonicstageasearlyasE15,graduallyincreasedthroughoutearlydevelopment,peakedatapproximatelybetweenpostnataldaysP6andP8,thenslightlydecreasedandremainedrelativelystableintheadult.

      DOMAIN:PDZ6mediatesinteractionwiththePDZrecognitionmotifofEFNB1andEPHB2andwiththeC-terminusofPPFIA1andPPFIA4.PDZ4andPDZ5mediateinteractionwithPRLHR(Bysimilarity).PDZ4andPDZ5mediateinteractionwiththeC-terminusofGRIA2andGRIA3.PDZ4,PDZ5andPDZ6mediatehomomultimers.PDZ7mediatesinteractionwithPDZdomainofGRASP1.PDZ7domainbindsCSPG4.PDZ6mediatesinteractionwiththeC-terminusofliprins-alpha.PDZ1,PDZ2andPDZ3mediateinteractionwiththePDZ-bindingmotifofFRAS1.

      SEQUENCESIMILARITIES:Contains7PDZ(DHR)domains.
      MolecularWeight~121kDaobserved
      PhysicochemicalInformation
      Dimensions
      MaterialsInformation
      MaterialsInformation
    售后保障
    螞蟻淘生物188,秉承螞蟻淘一貫的嚴謹態(tài)度,由螞蟻淘公司專業(yè)人員負責品控、采購、物流、銷售、售后,保障正品優(yōu)質。以“快速好省,為科研提供好產(chǎn)品、好價格”為理念,直接鏈接原廠家,從全國各地原制造商嚴格挑選188款科研精品,剔除品牌溢價,188生物新電商,把好的產(chǎn)品帶給科研!? 力求給你最優(yōu)質的商品。
  • Q:生物188產(chǎn)品正品保障嗎?
    A:生物188質量把控人員具有十年的從業(yè)經(jīng)驗,在業(yè)界享有良好的口碑;自營商城,直接從廠家采購, 自己的團隊負責國際物流和清關,中間沒有第三方,所有流程嚴格把控,100%保證正品,假一罰十。

    Q:下單后可以修改訂單嗎?
    A:下單后的商品付款之前可以修改;訂單付款成功,需要聯(lián)系我們客服進行修改;客服電話:4000-520-616

    Q:可以開發(fā)票嗎?
    A:本網(wǎng)站所售商品都是正規(guī)清關,均開具16%正規(guī)發(fā)票,發(fā)票金額含配送費金額,另有說明的除外。

    Q:商品幾天可以發(fā)貨?
    A:生物188商品,全部現(xiàn)貨銷售,付款后即可發(fā)貨,一般一周內送達!

    Q:如何聯(lián)系商家?
    A:有任何問題夠可以電話咨詢我們,全國24小時免費服務熱線:4000-520-616 或聯(lián)系我們的在線客服QQ:1570468124

    Q:收到的商品少了/發(fā)錯了怎么辦?
    A:同個訂單購買多個商品可能會分為一個以上包裹發(fā)出,可能不會同時送達,建議查看訂單詳情是否是 部分發(fā)貨狀態(tài);如未收到,可聯(lián)系在線客服或者致電4000-520-616。

    Q:退換貨/維修需要多長時間?
    A:一般情況下,退貨處理周期為客戶收到產(chǎn)品一個月內(以快遞公司顯示簽收時間為準),包裝規(guī)格、 數(shù)量、品種不符,外觀毀損、短缺或缺陷,請在收到貨24小時內申請退換貨;特殊商品以合同條款為準。

何為188

極簡而嚴謹,我們僅銷售188款生物醫(yī)學科研用品,款款都是爆款;因為少所以聚焦,聚焦甄選每一款產(chǎn)品,聚焦服務每一位客戶!

關注我們 :

點擊QQ聯(lián)系我們
生物188微信

關注188微信公眾號

獲取最新優(yōu)惠活動通知
  • 品質甄選,正品保證

  • 自營電商,廠家直采

  • 極簡主義,188精品