UniProtSummary | FUNCTION:SwissProt:P60880#t-SNAREinvolvedinthemolecularregulationofneurotransmitterrelease.Mayplayanimportantroleinthesynapticfunctionofspecificneuronalsystems.Associateswithproteinsinvolvedinvesicledockingandmembranefusion. SIZE:206aminoacids;23315Da SUBUNIT:PartoftheSNAREcorecomplexcontainingSNAP25,VAMP2andSTX1A.ThiscomplexbindsCPLX1.InteractswithTRIM9,RIMS1,SNAP25BPandHGS.BindsSTXBP6.FoundinaternarycomplexwithSTX1AandVAMP8.FoundinacomplexcontainingSYT1,SV2Bandsyntaxin-1(Bysimilarity). TISSUESPECIFICITY:Neuronsoftheneocortex,hippocampus,piriformcortex,anteriorthalamicnuclei,pontinenuclei,andgranulecellsofthecerebellum. PTM:Palmitoylated(Bysimilarity). SIMILARITY:SwissProt:P60880##BelongstotheSNAP-25family.&Contains2t-SNAREcoiled-coilhomologydomains. |