ThemonoclonalantibodyRG9-35recognizesmousegalectin-9,whichisa40kDamammalianlectinexpressedbylymphocytes,dendriticcells,granulocytes,eosinophils,astrocytes,endothelialcells,fibroblasts,andthymusepithelialcells.Galectin-9isaligandforTIM-3andinducesT?1celldeath.
Thispure-functionalgradeantibodyissuitedforcellculturefunctionalassays,forexample,blockingofreceptor-ligandbinding.