ExiTronPisapolymericiodine-basedcontrastagentofhighmolecularweightspecificallyformulatedforpre-clinicalcomputedtomography(CT).
ItshowsstrongX-rayabsorptionduetoitscovalentlyboundiodineatoms.Uponintravenousinjection,ExiTronPcirculatesinthebloodstreamforaprolongedtime.
Significantextravasationcanbeobservedinfenestratedbloodvesselsofinflamedtissueortumors.
ExiTronPismainlyexcretedviaglomerularfiltration(kidneys).
ExiTronPisindicatedforuseinCTofsmallanimals,forexamplemice,tofacilitatethevisualizationofthevasculature.
Examplesincludecontrast-enhancedangiography.